LaboratoryDesign|JULY|AUGUST 2016 11
manner. Here are three key design
features (and one principle) for initial
and ongoing flexibility:
1. Include open or sacrificial space
for new functions and associated
mechanical space: Locate shell space,
storage, office or other easily relocated
or converted functions in these areas,
plus mechanical shafts, rooms and roof
space for additional equipment.
2. Establish mechanical system
distribution with space for additional
systems: Once a lab is up and running,
renovations are disruptive, and even
without moving walls, re-routing or
adding ductwork or other mechanical
systems can shut down labs for weeks.
Designing the main distribution trunks
to accommodate additional new systems
in corridors or other non-lab space can
avoid re-routing or changes.
3. Consider structural capacity:
Special functions may require additional
loads, or more stringent vibration criteria
than for typical lab space. Locating heavy
or sensitive operations in smaller bays or
close to columns can significantly increase
load capacity and floor stiffness.
4. The overriding principle:
Flexibility for the next move. You
didn’t think this would be the last time
something changed, did you?
Considerations for future special lab
functions: The most common special
functions requested in our experience
include GMP and containment labs,
chemistry labs and vivaria. Each of
these is outside the norm for biology
lab space, but frequently demanded
on-site for the latest promising
scientific pathway. Following, we outline
considerations and design solutions for
The initial development of a promising
product may require on-site production
of small quantities for clinical trials,
particularly for cellular therapy or
other personalized medicine products
that may be less suitable or affordable
for traditional outsourcing to contract
research organizations (CROs).
Regulatory requirements typically
include compliance with current Good
Manufacturing Practices (cGMP).
Because bench top and production
work usually involve the same scientists,
remote locations are impractical.
Considerations for on-site production
• Containment/isolation or
• Low net to gross ratios (and
therefore large space needs) to
accommodate airlocks, separate
corridors and mechanical rooms.
• Separate mechanical systems for
regulatory compliance, including space
• Additional air handling
recirculation and/or exhaust capacity.
• Additional systems (steam, high
With VACUU·LAN® local vacuum networks, a quiet, in-lab, oil-free pump supports
multiple workstations in new labs or renovations. It’s a flexible, economical
approach to bench and fume hood vacuum supply.
• Modular – evolves with your needs
• “Green” – low energy use, right-sized
• Economical – fast, simple installation
• Safe – no inter-lab cross-contamination
• High performance – deep, stable vacuum
• Low maintenance – multi-year service
Modular Lab Vacuum Supply
VACUU·LAN® vacuum networks by VACUUBRAND
Watch our new 2 minute animation on our technology microsite,
www.vacuu-lan.com, or call us at 888-882-6730 E X P E
Proven worldwide in small teaching labs and
leading research institutions
LabDesign_vacuu-lan.indd 1 7/6/2016 4:51:28PM