The Agensys campus is a consolidation
of four different sites throughout the city of
Santa Monica in one research campus which
consists of flexible research labs, support spaces, manufacturing research, a GMP facility,
a pilot plant, a central plant, administrative
offices, a fitness center, a public café, a sculpture garden and a conferencing center. The
research labs support both biology and chemistry research with growth and flexibility for
HLW International, Los Angeles (architect
and lab planner); CRB Engineers, San Diego
(MEP); Structural Focus, Gardena, Calif.
Budget: $67 million
Size: 173,000-sf campus
Completion date: Q1 2013
As clients become more responsible for their
carbon footprint, there is greater concern and
care taken into consideration for planning
facilities that are environmentally responsible.
Agensys’ parent company, Astellas, takes great
strides to make all of their facilities worldwide
as environmentally friendly as possible. With
this project, HLW was asked to address the U.S.
Green Building Council’s LEED system.
HLW believes that in order to achieve LEED
status, the design must fully integrate architectural and mechanical systems. Involvement from
the early stages of design with CRB Engineers
Inc. was key to the success of designing and
constructing a facility that has gained LEED
Silver status. Business objectives and strategies
are completely defined at the beginning of the
design process so everyone is informed.
In consideration of the goals, the team
incorporated green solutions beginning with
re-use of the existing building structure.
Other features included:
• Shared support spaces, centrally located in
order to eliminate redundancy of spaces
and equipment. Groups can share centrally
located support spaces instead of having
their own dedicated spaces where equipment would only be used occasionally
which reduces the required square footage,
operating cost and encourages collaboration
between research groups.
• Flexible design supports future needs for
growth and change in technology. Each lab
was designed on the same module with the
same lab building services, which makes
relocating lab groups easy to optimize
adjacencies and performance. In turn, this
eliminates any construction and demolition
for future lab modifications.
• Moveable and flexible furniture allows for
re-use from other Agensys sites and flexibility in lab layouts. The same furniture system
is being utilized in other Agensys locations,
in order to reduce waste of unused furniture.
• The use of limited windows on the south
side of the facilities cuts down on air-conditioning costs. Lab and manufacturing areas
were located along south side of building.
• All lab lighting was tied to occupancy sen
sors so lights don’t come on
when rooms are unoccupied.
•Finishes such as Shaw Bio-life flooring and other cra-dle-to-cradle products were
specified throughout the
•Ample bike parking and
showers encourage local
employees to commute via
•A large outdoor eating area
eliminates HVAC required to
service café seating area.
The following MEP engineering measures were taken to
provide cost and energy-efficient savings:
• High-efficiency lighting
system with occupancy sensors in offices
and shutoff timer for labs (0.777 W/sf
instead of the Title 24 listed 1.4 W/sf).
• High-efficiency central chilled water plant
with York centrifugal chillers at 0.575 kw/
ton, oversized cooling towers with VSD fans
and high-efficiency boilers at 86%.
• Wall insulation increased to R- 19 (U-Factor
= .053 instead of the Title 24 listed U-Factor
• Roof insulation increased to R- 27 rigid/R- 30
batt (U-Factor = .033 instead of the Title 24
listed U-Factor = .065).
• VAV office and lab ventilation instead of
• Use of high-performance, low-e, insulated
glazing on east elevation (SHGC=0.29 and
Maximizing efficiency by design
continued on page 12
An existing 1930’s structure was re-adapted to create employee fitness center, public café and sculpture garden.
(Image: HLW/Yi Shen, AIA)
Flexible lab furniture placed in the center of the labs allows for easy configuration. (Image: HLW/Rami Barghout, PE)